Tocit 5 mg (Buy Tofacitinib)- 60 Tablets

Description

Introduction Of  Tocit 5 mg

Tocit 5 mg is a medication that is used to treat autoimmune disorders. Its generic name is Tofacitinib. Tocit 5 mg is an effective medication for the treatment of autoimmune diseases like rheumatoid arthritis, ulcerative colitis, and-psoriatic arthritis. It helps patients to manage their symptoms,  conditions, and side effects. It blocks certain parts of the immune system that are caused by this disease. 

Tocit 5 mg can be taken with other medication. Doctors prescribed it according to patient’s health conditions and for those patients who didn’t get any result in previous treatment.    

Tocit 5 mg Uses

Rheumatoid Arthritis

Tocit 5 mg is used for autoimmune disease. Rheumatoid arthritis is an autoimmune disease. Doctors prescribed tocit 5 mg to treat adults with moderate to severe autoimmune diseases. Doctors recommend this for those patients, who did not get any result from previous treatments. According to patients’ health, Doctors prescribed it with other medications like methotrexate or other nonbiologic disease-modifying antirheumatic drugs (DMARDs).  

Tocit 5 mg helps patients to decrease pain, swelling,   stiffness and helps to slow the joint damage.  

Psoriatic Arthritis

Tocit 5 mg use for the treatment of Psoriatic Arthritis. Doctors recommended this medication for adults with Psoriatic Arthritis. Doctors recommended this for those patients who were treated with methotrexate or other DMARDs but didn’t get any result. Psoriatic arthritis is a type of arthritis that causes inflammation and is often linked to psoriasis.It is the cause of joint pain, stiffness and swelling and it also affects the skin. 

Ulcerative Colitis

Tocit 5 mg is an effective treatment option for patients with moderate to severe active Ulcerative Colitis. It helps patients to manage symptoms, side effects and diseases. Ulcerative colitis mainly affects the colon and recturm. Patients experience symptoms like belly pain and diarrhea. They also suffer from discomfort and digestive issues.      

Pharmacology

Rheumatoid Arthritis is an autoimmune disease. It happens when there is a high level of protein that causes inflammation. These proteins include IL-7, IL-15, IL-21, IL-6, IFN-alpha, and IFN-beta. This imbalance causes pain and swelling in the joints.  These proteins also cause inflammation and damage in tissues. They activate  immune cells using a method called Janus kinase (JAK). And this is the cause of more joint problems.

Tocit 5 mg is a JAK inhibitor. It helps patients to block certain types of enzymes to slow down this process. Tocit 5 mg also helps to decrease  inflammation and joint damage.  It helps to make patients feel better and manage to reduce inflammation and improve health.    

Dosage & Administration

Rheumatoid Arthritis

• Doctors usually recommended 5 mg twice a day. In some cases 11 mg once a day. 
• Those patients are experiencing moderate to severe liver or kidney problems, 5 mg once a day is recommended for them. This is helpful to reduce the risk of harmful effects. The reduced dose is needed because the body clears the drug more slowly in these patients.   

For Psoriatic Arthritis

• Recommended dose is 5 mg twitch a day and 11 mg once a day if it is combined with nonbiologic DMARDs. 
• It can be taken similar to rheumatoid arthritis.  A reduced dose of 5 mg once daily is recommended for patients with renal or hepatic impairments.

For Ulcerative Colitis

• Doctors usually recommended 10 mg twitch a day for at least eight weeks. After this duration they may continue 5 mg or 10 mg twitch a day. It completely depends on the patient’s health and according to the doctor’s prescription. 
• Doctors recommend to stop this medication If patients does not get any improvement result after 16 weeks  
• Use the smallest dose that still works to manage the condition.

[Note: Do not start this treatment without following a registered doctor’s advice. It is essential to follow the prescription strictly]

Drug Interactions

The body breaks down Tocit 5 mg using an enzyme called CYP3A4. This might react with some other medicines.

Potent CYP3A4 Inhibitors (e.g., Ketoconazole)

When taken with strong CYP3A4 inhibitors, the Tocit 5 mg dose should be lowered to 5 mg once daily. This helps prevent high drug levels in the body. The reduced dose keeps it safe for use with these other medicines.

Moderate CYP3A4 Inhibitors and Potent CYP2C19 Inhibitors (e.g., Fluconazole)

Take a 5 mg dose once daily when using drugs that strongly affect CYP2C19 and moderately affect CYP3A4.

Potent CYP3A4 Inducers (e.g., Rifampin)

Strong CYP3A4 inducers can make Tocit 5 mg less effective by speeding up its breakdown. It lowers its level in the body. The doctor may need to adjust the Tocit 5 mg dose or try another treatment. 

Side Effects

Common Side Effects Of Tocit 5 mg

• Upper respiratory tract infections 
• Headaches
• Diarrhea
• Nasopharyngitis 

Pregnancy and Lactation

• Tocit  5 mg is in pregnancy Category C. Category C means there is not enough study on its safety on this topic.  It should only be used if the benefits are greater than the risks to the baby.
• It is not clear if Tocit 5 mg passes into human breast milk. Since many medications do get into breast milk and can cause problems for nursing babies, a doctor may recommend stopping the medication or stopping breastfeeding. The decision will depend on how important the drug is for the mother’s health.

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