Olaparib
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Showing all 2 results
Olaparib is a targeted cancer therapy used primarily in the treatment of certain types of ovarian, breast, pancreatic, and prostate cancers. Marketed under the brand name (Lynparza), Olaparib is an oral medication classified as a PARP inhibitor. It works by blocking enzymes in cancer cells that help repair damaged DNA, causing the cancer cells to die.
Patients who seek to buy Olaparib online often do so for its proven effectiveness in managing advanced cancers with BRCA mutations. As a trusted oncology medicine, Olaparib plays an important role in personalized cancer care today.
Olaparib (Lynparza) was developed by AstraZeneca and approved by the U.S. FDA in 2014. The medicine represents a breakthrough in oncology, especially for cancers associated with inherited BRCA gene mutations. Originally researched for ovarian cancer, its indications have expanded based on positive clinical outcomes.
Olaparib’s development is a landmark in precision medicine. Its success has paved the way for other PARP inhibitors and targeted therapies.
Olaparib is used alone or in combination with bevacizumab (Avastin) to help maintain the response of certain types of ovarian (female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and peritoneal (layer of tissue that lines the abdomen) cancer in people who have completely responded or partially responded to their first or later chemotherapy treatments.
Olaparib is also used to treat certain types of breast cancer that has spread to other parts of the body and has not improved or has worsened after treatment with other therapies. It is also used to treat certain types of early breast cancer in people who have already been treated with surgery and other chemotherapy treatments. Olaparib is also used to treat a certain type of prostate cancer that has spread to other parts of the body, no longer responds to medical or surgical treatments to lower testosterone levels, and has progressed after treatment with enzalutamide (Xtandi) or abiraterone (Yonsa, Zytiga). It is also used in combination with abiraterone and prednisone to treat a certain type of prostate cancer that has spread to other parts of the body and no longer responds to medical or surgical treatments to lower testosterone levels. Olaparib is also used to help maintain the response of a certain type of pancreatic cancer that has not spread or progressed after the first chemotherapy treatment. Olaparib is a polyadenosine 5′-diphosphoribose polymerase (PARP) enzyme inhibitor. It works by killing cancer cells.
Doctors prescribe Olaparib to treat:
It is typically used in patients whose cancer has a BRCA gene mutation. These mutations impair the body’s ability to repair DNA damage naturally, which is where Olaparib helps.
To understand how Olaparib works, you need to understand PARP enzymes. PARP enzymes help repair damaged DNA in cells. Cancer cells rely heavily on PARP for survival if their BRCA genes are defective. Olaparib’s mechanism of action involves blocking PARP enzymes, which leads to cancer cell death.
This makes Olaparib highly effective in BRCA-mutated cancer types while sparing healthy cells, reducing collateral damage common in traditional chemotherapy.
Olaparib comes as a tablet to take by mouth twice daily with or without food. Try to space your doses about 12 hours apart. Take olaparib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take olaparib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the tablets whole; do not crush, chew, divide, or dissolve them.
Your doctor may decrease your dose of olaparib or tell you to stop taking olaparib for a period of time during your treatment. This will depend on how well the medication works for you and any side effects you may experience. Be sure to tell your doctor how you are feeling during your treatment with olaparib.
Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with olaparib. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website https://www.fda.gov/Drugs/DrugSafety/ucm085729.htm to obtain the Medication Guide.
Olaparib is indicated to treat breast cancer, ovarian cancer, fallopian tube cancer, peritoneal cancer, pancreatic cancer, and prostate cancer.
At Unit Pharmacy, we offer high-quality Olaparib medicines to support advanced cancer treatment. Choose from two trusted brands:
Manufactured by a reputed pharmaceutical company, Olanib is a reliable generic alternative to Lynparza, used in treating ovarian, breast, prostate, and pancreatic cancers with BRCA mutations.
Olaparix offers effective PARP inhibition therapy at an affordable price. It is prescribed for patients needing a consistent, high-quality supply of Olaparib.
Both products are available for international shipping with verified quality assurance and competitive pricing.
This medication may also be prescribed for other uses; ask your doctor or pharmacist for more information. Outside of its FDA-approved uses, Olaparib is being studied for other cancers including:
Researchers are exploring its effectiveness in combination with immunotherapy and other targeted agents.
Before starting Olaparib, tell your doctor if you have:
There are no strict dietary restrictions, but patients are advised to:
Again, grapefruit should be avoided due to its interaction with Olaparib’s mechanism of action.
In December 2014, olaparib was approved for use as a single agent by the European Medicines Agency (EMA) in the European Union and by the Food and Drug Administration (FDA) in the United States. Olaparib was developed and first dosed into patients by the UK-based biotechnology company, KuDOS Pharmaceuticals, that was founded by Stephen Jackson of Cambridge University, UK.Since KuDOS was acquired by AstraZeneca in 2006, the drug has undergone clinical development by AstraZeneca and Merck & Co.
The FDA approved Olaparib for ovarian cancer in December 2014, marking it the first PARP inhibitor on the market. Since then, it has gained approval for:
These approvals are based on extensive clinical trials demonstrating improved progression-free survival.
Olaparib mechanism of action is centered on PARP inhibition. Cancer cells with BRCA1 or BRCA2 mutations struggle to repair double-strand DNA breaks. Olaparib inhibits PARP enzymes, causing unrepaired DNA damage, which leads to apoptosis (cell death).
This mechanism is what gives Olaparib its selectivity for cancer cells and contributes to fewer side effects compared to conventional chemotherapy.
Olaparib may cause side effects. Common side effects of Olaparib along with its needed effects, a medicine may also cause some unwanted effects. Although not all of these side effects may occur, they may require medical attention if they do occur.
Check with your doctor immediately if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
The standard Olaparib dose is taken orally twice a day. However, your doctor may adjust it based on your condition, lab results, and tolerance.
Olaparib dosing may be reduced if you experience side effects like anemia or neutropenia. In such cases, doctors may recommend Olaparib dose reduction or temporary discontinuation.
Take Olaparib oral tablets at consistent times each day. It is crucial not to skip doses or take more than prescribed. Swallow the tablet whole with water. If you feel nauseous, discuss with your doctor about anti-nausea medication.
Knowing how to take Olaparib properly improves treatment outcomes and minimizes risks.
If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at once. Contact your healthcare provider if you’re unsure what to do.
Missing multiple doses can reduce the effectiveness of treatment, so try to take Olaparib on a strict schedule.
Olaparib indications include treatment of:
These are often cancers resistant to traditional therapies, and Olaparib offers a promising alternative.
Olaparib brand name is (Lynparza), developed by AstraZeneca. In some markets, it may be found under other manufacturer names depending on the region. Common Olaparib other names include:
You may find various Olaparib brands available through licensed pharmacies, depending on the manufacturer.
The cost of Olaparib varies significantly depending on the country, supplier, and insurance coverage. On average, a month’s supply can range from $3,000 to $15,000 in the USA.
If you’re looking to buy Olaparib online, trusted suppliers like Unit Pharmacy offer competitive Olaparib price options for international buyers. You can explore different Olaparib brands available at affordable prices.
You can also compare Olaparib cost with branded alternatives to ensure you are receiving the best value.
Many patients now buy Olaparib online from reputable sources like Unit Pharmacy to access high-quality generic options at a lower price. Ensure that the seller is licensed, transparent, and offers authentic medicines.
When searching for Olaparib buy options, consider delivery time, payment security, and product authenticity.
Olaparib is a life-changing medication that offers real hope for people battling advanced cancers. Whether you’re dealing with breast cancer, ovarian cancer, prostate cancer, or another BRCA-mutated cancer, Olaparib provides a targeted approach with proven outcomes.
Understanding how does Olaparib work, its indications, side effects, and how to take it properly is key to successful treatment. If you’re looking for trustworthy and affordable options to buy Olaparib online, Unit Pharmacy is here to help.
Olaparib has transformed the cancer care landscape—and for many, it’s a symbol of hope and survival.
