Barinib 2 Mg (Baricitinib) – 30 Tables

Overview of Barinib 2 mg (Baricitinib)

Barinib is a prescription medicine that contains Baricitinib, a drug primarily used for treating rheumatoid arthritis in adults. It comes in two strengths:

• Barinib 2 mg Tablets: Each tablet contains 2 mg of Baricitinib.

Barinib 2 mg (Baricitinib)

Barinib  2 mg (Baricitinib) is primarily prescribed for individuals with moderate to severe rheumatoid arthritis .Barinib 2 mg is a very effective medication. Barinib 2 mg offers a hopeful alternative that can improve joint functions and overall quality of life. It is used to treat autoimmune disorders. It is specially used for the treatment of moderate to severe rheumatoid arthritis and alopecia areata. The immune system mistakenly targets healthy cells in the body and attacks them. It causes damage to tissues and organs. These conditions are called Autoimmune diseases.    

Barinib  2 mg (Baricitinib) is a type of medicine that is a part of Janus kinase (JAK) inhibitor. These medications help patients to reduce inflammation and make it easier for patients to manage the symptoms of autoimmune diseases. Barigen mainly works by targeting the JAK enzymes that cause inflammation. 

Barinib 2 mg helps control chronic inflammation. Barigen improves patients’ conditions like rheumatoid arthritis. This treatment is very effective for those patients who did not get any result from other treatments.

Rheumatoid arthritis

Rheumatoid arthritis is a long-term condition. Patients experienced joint pain,  inflammation, pain, and stiffness in the joints. Immune system usually fights against Infections. But in this case Of Rheumatoid arthritis, Immune system mistakenly attacks the body’s own tissues and joints. It can cause swelling, damage, and limit movement if left untreated. Barinib 2 mg helps to reduce the inflammation and protects the joints from further damage.

Baricitinib blocks certain molecules called STATs (Signal Transducers and Activators of Transcription).  This is  responsible for triggering inflammation in the cells. By blocking the activation of STATs, Barinib helps in reducing the symptoms and slowing the progression of rheumatoid arthritis, allowing patients to manage their condition more effectively.

Mechanism of Action 

Baricitinib is the main ingredient of Barinib 2 mg. It blocks two enzymes in the body called JAK1 and JAK2. This helps reduce inflammation and pain. When enzymes become overly active, they cause the immune system to attack the body’s own tissues. This leads to inflammation and pain. Conditions like rheumatoid arthritis often result from this immune response. Baricitinib helps reduce the activity of these enzymes, which controls the inflammation and reduces the joint pain, stiffness, and swelling caused by RA. 

Safety Information

Barinib 2 mg (Baricitinib) can increase the risk of infections like colds. This risk is higher than when a person takes a placebo. It’s important to know about this risk,  benefits, especially for those with ongoing infections before starting this treatment. When Barinib is taken with Methotrexate, it can cause more infections than when barinib is used alone. 

If an infection happens during treatment, careful monitoring is needed.  If the patient does not respond to standard treatment then doctors might advise them to stop the treatment for a while. 

[Warning: Do not start this treatment without doctors permission]

Barinib 2 mg Uses

Baricitinib is used to treat moderate to severe active rheumatoid arthritis in adults. It is particularly recommended for patients who have not responded well to other disease-modifying anti-rheumatic drugs (DMARDs) or cannot tolerate them. Baricitinib can be used on its own (monotherapy) or in combination with Methotrexate, another drug used to treat rheumatoid arthritis.

When taken with strong OAT3 inhibitors (like probenecid), a lower dose of Baricitinib (2 mg once daily) is recommended to avoid increased drug exposure.

Precautions

Infection Monitoring: It’s recommended to check Infection before starting the treatment.If a patient has a past history of infection they should tell the doctor about this. Check for tuberculosis (TB) and other infections. 

Blood Monitoring: This treatment can affect blood cells levels. It is important to  check the blood cells before the treatment, and also during the treatments. 

Liver and Kidney Monitoring: Regular testing is necessary for patients with pre-existing liver or kidney issues.

Side Effects 

Common Side Effects Of  Barinib 2 mg (Baricitinib)

These are the side effects most frequently reported by patients taking Barinib:

• Increased LDL Cholesterol
• Upper Respiratory Tract Infections
• Nausea
• Headache
• Fatigue
• Increased Liver Enzymes
• Abdominal Pain

• Diarrhea
• Skin Reactions
• Acne
• Increased Creatinine Levels
• Infection Risk

Serious Side Effects Of Barinib 2 mg

• Infections
• Blood Clots
• Gastrointestinal Perforation
• Changes in Blood Cell Counts
• Liver Problems
• Reactivation of Viruses

Dosage and Administration

It is recommended for the patients to follow their doctors prescriptions for dose. Doctors prescribed it according to patients ‘ health conditions or health history.  Usually for most patients prescribed 4 mg in a day. In certain cases, such as for patients aged 75 years or older or those with a history of frequent infections, a lower dose of 2 mg once daily is recommended. If any patients take good control of their disease then they can reduce their dose by their doctor. 

For patients with renal impairment (creatinine clearance between 30 and 60 mL/min), the recommended dose is 2 mg once daily. Baricitinib is not recommended for patients with creatinine clearance below 30 mL/min.

No dose adjustments are required for patients with mild to moderate hepatic impairment. However, Baricitinib is not recommended for patients with severe liver problems.

conclusions

Barinib 2 mg is a medication that is used to treat moderate to severe rheumatoid arthritis and alopecia areata in adults. This treatment reduces inflammation and controls the immune system’s response to prevent joint damage. Regular monitoring is essential during these treatments. Doctors should check Blood levels and infections, so that the treatment continues without any difficulties.