Caboxen 80 Mg (Cabozantinib) – 30 Capsules

 Caboxen 80 mg (cabozantinib cost) 

Caboxen 80 mg is a drug and its generic name is Cabozantinib. It is a tyrosine kinase Inhibitor. Caboxen 80 Mg ( Cabozantinib cost) is used for the treatment of severe types of cancer and chemotherapy drugs. It works to block specific cancer cells. And stop them from growing and spreading.  

Especially for Renal Cell Carcinoma (RCC) and Hepatocellular Carcinoma (HCC) 

Renal Cell Carcinoma: Coboxen is used for the treatment of Renal Cell Carcinoma (RCC). Patients who are suffering from RCC, can take this treatment.

Hepatocellular Carcinoma: Cabozantinib is used for the treatment of Hepatocellular Carcinoma (HCC) for those patients who have been previously treated with sorafenib. 

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Caboxen 80 mg (cabozantinib cost) 

Price: $225.00

Quantity: 30 Tablet

Product Features of Caboxen 80 mg

Mechanism of Action

Cabozantinib works to block signals in cancer cells so that they can not spread or grow. It targets specifically some proteins in the cancer cell that help to increase the growth of cancer. These  resentors are MET, VEGFR-1, -2, and -3, AXL, RET, ROS1, TYRO3, MER, KIT, TRKB, FLT-3, and TIE-2. 

This treatment is more effective than traditional chemotherapy.

Cabozantinib Uses

Metastatic Medullary Thyroid Cancer (MTC)

 Metastatic Medullary Thyroid Cancer is difficult to treat. Caboxen 80 mg (Cabozantinib cost) is used for the treatment of  Metastic Medullary Thyroid Cancer. and It can be spread to other parts of the body. And It is a rare form of thyroid cancer. 

Advanced Renal Cell Carcinoma (RCC) 

 Cabozantinib is used for the treatment of advanced renal cell carcinoma. Its treatment is effective and patients get significant results and improved.   

Hepatocellular Carcinoma (HCC)  

Cabozantinib is used for the treatment of Hepatocellular Carcinoma (HCC). Patients who already treated with sorafenib but did not get improved. It can be an alternative option for them. Cabozantinib targets some specific cancer cells and blocks them from growing or spreading. 

Dosage and Administration

Dosage

Doctors recommended usually 60 mg Cabozantinib (caboxen 80 mg) once a day.  But all patients’ conditions are not the same. So the dose also depends on the patient’s conditions. Doctors adjust the dose of caboxen 80 mg according to the patient’s health condition. Doctors adjust the medicine according to patients tolerability and respond to the treatments.  

Administration

Cabozantinib (caboxen 80 mg) has to take  without food. It should be in an empty stomach. Swallowed the whole capsule with water. Do not crush it. Take this medicine before 1 hour or after two hours of eating.  

Missed Doses

If you miss a dose of caboxen  80 mg and you have to take the  next dose in 12 hours. Then do not take the dose. And also do not double the dose with the next dose. Take the next doses at regular times. 

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Side Effects of Cabozantinib (caboxen 80 mg)

Side Effects of Cabozantinib (Caboxen 80 mg)

• Common Side Effects 

This side effect is shown in 30% of the patients, Increased liver enzymes problems, Diarrhea, Low calcium levels, Mouth sores, Hand-foot syndrome like (skin rash, swelling, redness, pain, or peeling of palms and soles), Weight loss, Decreased appetite, Nausea, Fatigue, Oral pain, Neutropenia, Low platelets, Taste changes, Hair color changes, High blood pressure.

• Less Common Side Effects

Low phosphorus levels, Abdominal pain, Constipation, High bilirubin levels, Vomiting, Weakness, Voice changes, Dry skin, Rash, Low magnesium levels, Headache, Low potassium levels, Hair loss, Dizziness, Joint pain, Difficulty swallowing, Muscle spasms, Indigestion, Skin redness, Low sodium levels.

Serious Complications:

• Perforation in the gastrointestinal tract
• Severe bleeding
• Impaired wound healing and fistulas
• Blood clots

If you experience any of these symptoms please contact your doctor or seek medical help.  

If you feel chest pain or shortness of breath, please immediately go for medical help. Or, any patients experience fever 100.4°F or higher, severe headache, numbness, difficulty speaking, tingline, immediately contact your doctors. 

Precautions and Considerations

Before initiating treatment with Cabozantinib (caboxen 80 mg), healthcare providers should consider several precautions and patient-specific factors:

• Hypertension: Cabozantinib can cause hypertension, including hypertensive crisis. This can be increase the risk of Blood pressure. So patient have to checkup regularly. The patient requires antihypertensive therapy.
• Hemorrhage: Severe and fatal hemorrhagic events have been reported with Cabozantinib (caboxen 80 mg). Patients with a history of bleeding disorders or recent bleeding episodes should be monitored closely. gastrointestinal ulcers should be monitored closely.
• Wound Healing: Cabozantinib may impair wound healing, and elective surgeries should be scheduled with caution. Treatment should be interrupted at least 28 days before elective surgery, including dental procedures.
• Renal and Hepatic Impairment: Dosage adjustments may be necessary in patients with impaired renal or hepatic function. Close monitoring of renal and hepatic function tests is recommended during treatment.
• Pregnancy and Contraception: Cabozantinib can cause fetal harm when administered to pregnant women. Effective contraception should be used during treatment and for at least 4 months after the final dose. Women of reproductive potential should avoid pregnancy during this period.

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Drug Interactions

CYP3A4 primarily mediates the metabolism of cabozantinib, and co-administration with strong CYP3A4 inhibitors or inducers can alter cabozantinib (caboxen 80 mg) plasma concentrations, potentially affecting its efficacy and safety.

Patients should avoid grapefruit products and other strong CYP3A4 inhibitors during Cabozantinib (caboxen 80 mg)  treatment unless medically necessary and closely monitored.

Monitoring and Follow-Up

Patients undergoing treatment with Cabozantinib require regular monitoring to assess treatment response, manage side effects, and ensure safety:

• Laboratory Tests: Regularly monitor liver function tests (ALT, AST), renal function (serum creatinine, urine protein), complete blood count (CBC), and blood pressure. 
• Imaging Studies: Radiographic imaging, such as CT scans or MRI, may be used to assess tumor response and disease progression. 
• Patient Education: Patients should be educated about the signs and symptoms of potential side effects, including hypertension, bleeding, and gastrointestinal complications. Prompt reporting of any new or worsening symptoms is essential for timely intervention.

Conclusion

Cabozanix 80 mg (Cabozantinib) represents a significant advancement in the treatment of metastatic thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma. Its targeted mechanism of action offers the potential for improved outcomes and reduced side effects compared to traditional chemotherapy.

Healthcare providers play a crucial role in monitoring patients, managing side effects, and optimizing treatment strategies to achieve the best possible outcomes for patients undergoing Cabozantinib therapy.

Cabozantinib brands name

Storage and Availability

Store cabozantinib (caboxen 80 mg) capsules below 30°C in a cool, dry place, away from direct sunlight, and out of the reach of children.. The medication is available for delivery worldwide, including countries such as the United States, United Kingdom, Saudi Arabia, Dubai, Kuwait, Qatar, Philippines, Nepal, Malaysia, Indonesia, and more.