Tofaxen 5 Mg (Tofacitinib) – 60 Tablets

Introduction to Tofaxen 5 mg

Tofaxen 5 mg, a generic formulation of Tofacitinib, is a targeted synthetic disease-modifying antirheumatic drug (tsDMARD) widely used in the management of autoimmune diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ulcerative colitis (UC). Manufactured by Everest Pharmaceuticals Ltd, this medication provides a more affordable yet equally effective alternative to brand-name versions like Xeljanz.

At UnitPharmacy, we provide Tofaxen 5 mg at competitive prices with full transparency, authentic sourcing, and global delivery. This page will walk you through everything you need to know before you buy, including mechanism of action, dosage, side effects, warnings, and user experiences.

What is Tofaxen 5 mg?

How Tofaxen 5 mg Works (Mechanism of Action)

Tofacitinib, the active ingredient in Tofaxen 5 mg, selectively inhibits Janus Kinases (JAK1 and JAK3). These are enzymes responsible for the signaling pathways involved in immune cell activity. By blocking these pathways, the drug suppresses cytokine-mediated inflammation.

This unique mechanism makes Tofaxen especially useful for chronic autoimmune conditions where the body’s immune system attacks its own tissues.

Approved Indications & Therapeutic Uses

Tofaxen 5 mg is prescribed for the treatment of:

• Rheumatoid Arthritis (RA) in adults with an inadequate response to methotrexate
• Psoriatic Arthritis (PsA) in combination with other DMARDs
• Ulcerative Colitis (UC) in adults with moderate to severe symptoms
• Off-label use for ankylosing spondylitis (AS) and other inflammatory autoimmune conditions under specialist supervision

This oral Janus Kinase (JAK) inhibitor works by blocking enzymes that contribute to the inflammatory process, thereby reducing swelling, pain, and joint damage.

Off-Label Uses & Research Areas

Ongoing studies are exploring Tofacitinib for:

• Chronic graft-versus-host disease (cGVHD)
• Alopecia areata (autoimmune hair loss)
• Other rare autoimmune conditions resistant to standard therapies.

Dosage & Administration Guidelines

Always follow your doctor’s instructions. The most commonly prescribed dosage of Tofaxen 5 mg is:

Note: Dosage may be adjusted in case of renal impairment, hepatic dysfunction, or concurrent CYP3A4 inhibitors use.

How Tofaxen Works in the Body

• Metabolized mainly by CYP3A4 enzymes, with minor involvement of CYP2C19.
• Starts to reduce inflammation in 2–12 weeks.
• Full therapeutic effect can be seen in 3–6 months.
• Provides long-term disease control when taken regularly.

Benefits of Tofaxen 5 Mg

• Reduces joint pain and stiffness for improved mobility.
• Helps prevent joint damage and disability.
• Improves bowel health in ulcerative colitis patients.
• Convenient oral dosing compared to injectable biologics.
• More affordable than the brand-name Xeljanz.

FDA Boxed Warnings & Safety Profile

The FDA boxed warning for Tofacitinib includes:

• Increased risk of MACE (major adverse cardiovascular events) such as heart attack and stroke.
• Higher risk of certain cancers including lymphoma and skin cancer.
• Increased chance of blood clots in the lungs and deep veins.

These warnings are based on data from the ORAL Surveillance study in rheumatoid arthritis patients.

Side Effects of Tofaxen 5 mg

Common side effects:

• Headache
• Diarrhea
• Nasopharyngitis
• Hypertension
• Nausea

Serious risks:

• Serious infections (e.g., tuberculosis, pneumonia)
• Increased risk of blood clots
• Elevated liver enzymes
• Herpes zoster (shingles)
• Malignancy risk with long-term use

Promptly report any unusual symptoms to your physician. Regular monitoring is essential while using this medication.

Warnings & Precautions

Before starting Tofaxen 5 mg, inform your healthcare provider if you:

• Have a history of chronic infections or tuberculosis
• Are pregnant or planning pregnancy
• Have liver/kidney impairment
• Are receiving immunosuppressants or biologic agents
• Have risk factors for cardiovascular diseases or thrombosis

Live vaccines should be avoided during treatment.

Drug Interactions

Tofaxen 5 mg can interact with:

• CYP3A4 inhibitors (e.g., ketoconazole): May increase drug levels
• CYP3A4 inducers (e.g., rifampin): May reduce efficacy
• Biologics (e.g., adalimumab, infliximab): Increased risk of infection
• Immunosuppressants (e.g., azathioprine, cyclosporine): Avoid co-use

Always inform your healthcare provider about all the medications and supplements you’re taking.

Monitoring Requirements

• CBC (Complete Blood Count) – Before and during treatment.
• Lipid profile – 4–8 weeks after starting therapy.
• Liver enzymes – To check for liver injury.
• TB screening before starting therapy.

Tofaxen vs Other Treatments

Tofacitinib vs TNF inhibitors:

• TNF inhibitors (e.g., adalimumab, etanercept) require injections and are costlier.
• Tofacitinib is an oral small molecule with quicker onset for some patients.
• Doctors may recommend Tofaxen for patients not responding to methotrexate or TNF inhibitors.

Storage, Handling & Disposal

• Store below 30°C in a dry place away from sunlight
• Keep out of reach of children
• Do not use expired tablets
• Do not flush medication; follow local pharmaceutical waste disposal rules

Pricing & Availability

• Tofaxen 5 mg is just $ 45.00 USD in Unit Pharmacy.
• Tofaxen 5 mg price is significantly lower than Xeljanz 5 mg cost. 
• Available in multiple markets through Unit Pharmacy.

Comparison Table: Tofaxen vs Xeljanz

Buy Tofaxen Online from Unit Pharmacy

Looking for a reliable and affordable source to buy Tofaxen 5 mg online? Unit Pharmacy offers 100% genuine Tofacitinib tablets manufactured by Everest Pharmaceuticals Ltd., trusted for quality and effectiveness in managing rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Why buy from Unit Pharmacy?

• Authentic Tofacitinib 5 mg tablets from Everest Pharmaceuticals Ltd.
• Fast and secure worldwide delivery
• Transparent pricing with no hidden charges
• Discreet packaging

You can order securely through Unit Pharmacy to begin managing your condition more effectively. With genuine Tofaxen 5 mg!

Shop Now at Unit Pharmacy

Expert Advice & Resources

Stay informed about your treatment. Consult:

• Your rheumatologist or gastroenterologist for personalized medical advice
• Resources from American College of Rheumatology (ACR)
• Patient guides from FDA, WHO, and EMA

These trusted bodies provide valuable updates on JAK inhibitor safety, alternatives, and treatment guidelines.

Customer Reviews & Success Stories

Emily R.
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“Tofaxen 5 mg has truly improved my rheumatoid arthritis symptoms. After just a few weeks, my joint pain and stiffness decreased significantly. I highly recommend it!”

James T.
⭐️⭐️⭐️⭐️
“Affordable and effective! I switched from Xeljanz to Tofaxen and didn’t notice any difference in quality. Plus, ordering from Unit Pharmacy was easy and fast.”

Sophia M.
⭐️⭐️⭐️⭐️⭐️
“Managing my psoriatic arthritis feels more manageable now. Tofaxen has helped reduce inflammation and improved my daily mobility. Grateful for this medicine.”

Share Your Story!
We love hearing from our customers. If you have a success story or feedback about Tofaxen 5 mg, please contact us or leave a review.

Conclusion : Tofaxen Everything in a short.

Tofaxen 5 mg (Tofacitinib) is a powerful and reliable JAK inhibitor used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It offers targeted relief, slows disease progression, and enhances daily function. Trusted by specialists and manufactured by Everest Pharmaceuticals, Tofaxen 5 mg is your affordable choice—available at UnitPharmacy with global delivery.

Choose Tofaxen. Take control of your health.

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